RAF Typhoon FGR4s have conducted a mission with French aircraft in a coordinated attack against an underground arms cache in Syrian territory used by the Daesh militant organization, according to the UK Ministry of Defence.
The location, located using surveillance, was assessed as storing arms and explosives, the release indicated, and was positioned in mountains just above the ancient city of Palmyra in Syria's central region.
"Our aircraft employed Paveway IV guided bombs to strike a series of entry passages providing entry to the facility... initial indications suggest the target was engaged successfully," the ministry announced.
There was no indication of any harm to civilians in the strike late on Saturday and all the aircraft made a safe return, the defence officials confirmed.
The British jets were backed up by a Voyager aerial refuelling aircraft.
IS - also known as the so-called Islamic State - imposed militant control over large swathes of Iraq and Syria until 2019.
"This strike demonstrates our UK leadership, and commitment to stand shoulder to shoulder with our partners, to eradicate any revival of Daesh and their violent and radical beliefs in the Middle East," UK Defence Secretary John Healey stated.
RAF aircraft have carried out overwatch operations over Syria to "prevent any efforts to regroup" of IS following its military defeat at the battle of Baghuz in 2019, the ministry said.
"I extend gratitude to all the members of British forces who took part in this mission for their skill and their bravery," Healey commented. "Including them were numerous British troops on duty over the holidays. This mission, to remove militants who threaten our security, demonstrates how UK forces are prepared to act, throughout the year, keeping Britain secure within its borders and strong abroad."
Last December, the United States armed forces conducted what it termed a "major assault" on Islamic State objectives in the country, subsequent to an ambush killed two US servicemembers and a local interpreter in the Palmyra area.
The United Nations says Daesh still boasts an estimated 5,000 to 7,000 combatants in Syria and Iraq.